The ADA4255 is a precision programmable gain instrumentation amplifier (PGIA) with integrated bipolar charge pumps. With its integrated charge pumps, the ADA4255 internally produces the high voltage bipolar supplies needed to achieve a wide input voltage range (38 V typical with VDDCP = 5 V) without lowering input impedance. The charge pump topology of the ADA4255 allows channels to be isolated with only low voltage components, reducing complexity, size, and implementation time in industrial and process control systems.The zero drift PGIA topology of the ADA4255 self calibrates dc errors and lower frequency 1/f noise, achieving excellent dc precision over the entire specified temperature range. The combination of 36 precision gains ranging from 1/16 V/V to 176 V/V within the ADA4255 and high voltage, high impedance inputs allow a wide range of inputs to be scaled to the range of the analog-to-digital converter (ADC). By integrating all gain setting and level shifting resistors, the ADA4255 achieves excellent common-mode rejection ratio (CMRR) performance (111 dB minimum at G = 1 V/V) and extremely low gain drift (±1 ppm/°C maximum). This high level of precision maximizes dynamic range and greatly reduces calibration requirements in many applications.The ±60 V input protection, integrated electromagnetic interference (EMI) filtering and various safety features make the ADA4255 an ideal choice for robust industrial systems. Seven general-purpose input and output (GPIOx) pins, which can be configured to provide various special functions, are included in the ADA4255. An excitation current source output is available to bias sensors such as resistance temperature detectors (RTDs).The ADA4255 is specified over the −40°C to +105°C temperature range and is offered in a compact 5 mm × 5 mm, 28-lead LFCSP.APPLICATIONSUniversal process control front endsData acquisition systemsTest and measurement systemsSystem power monitoring