The AD8227 is a low cost, wide supply range instrumentation amplifier that requires only one external resistor to set any gain between 5 and 1000. The AD8227 is designed to work with a variety of signal voltages. A wide input range and rail-to-rail output allow the signal to make full use of the supply rails. Because the input range can also go below the negative supply, small signals near ground can be amplified without requiring dual supplies. The AD8227 operates on supplies ranging from ±1.5 V to ±18 V (2.2 V to 36 V single supply).The robust AD8227 inputs are designed to connect to real-world sensors. In addition to its wide operating range, the AD8227 can handle voltages beyond the rails. For example, with a ±5 V supply, the part is guaranteed to withstand ±35 V at the input with no damage. Minimum as well as maximum input bias currents are specified to facilitate open wire detection. The AD8227 is ideal for multichannel, space-constrained applications. With its MSOP package and 125°C temperature rating, the AD8227 thrives in tightly packed, zero airflow designs.The AD8227 is available in 8-pin MSOP and SOIC packages. It is fully specified for −40°C to +125°C operation.For a similar instrumentation amplifier with a gain range of 1 to 1000, see theAD8226.ApplicationsIndustrial process controlsBridge amplifiersMedical instrumentationPortable data acquisitionMultichannel systems