The AD8221 is a gain programmable, high performance instrumentation amplifier that delivers the industry’s highest CMRR over frequency in its class. The CMRR of instrumentation amplifiers on the market today falls off at 200 Hz. In contrast, the AD8221 maintains a minimum CMRR of 80 dB to 10 kHz for all grades at G = 1. High CMRR over frequency allows the AD8221 to reject wideband interference and line harmonics, greatly simplifying filter requirements. Possible applications include precision data acquisition, biomedical analysis, and aerospace instrumentation.Low voltage offset, low offset drift, low gain drift, high gain accuracy, and high CMRR make this part an excellent choice in applications that demand the best dc performance possible, such as bridge signal conditioning.Programmable gain affords the user design flexibility. A single resistor sets the gain from 1 to 1000. The AD8221 operates on both single and dual supplies and is well suited for applications where ±10 V input voltages are encountered.The AD8221 is available in a low cost 8-lead SOIC and 8-lead MSOP, both of which offer the industry’s best performance. The MSOP requires half the board space of the SOIC, making it ideal for multichannel or space-constrained applications.Performance is specified over the entire industrial temperature range of −40°C to +85°C for all grades. Furthermore, the AD8221 is operational from −40°C to +125°C*.ApplicationsWeigh scalesIndustrial process controlsBridge amplifiersPrecision data acquisition systemsMedical instrumentationStrain gagesTransducer interfaces