The AD8278 and AD8279 are general-purpose difference amplifiers intended for precision signal conditioning in power critical applications that require both high performance and low power. The AD8278 and AD8279 provide exceptional common-mode rejection ratio (80 dB) and high bandwidth while amplifying input signals that are well beyond the supply rails. The on-chip resistors are laser trimmed for excellent gain accuracy and high CMRR. They also have extremely low gain drift vs. temperature.The common-mode range of the amplifier extends to almost triple the supply voltage (for G = ½), making the amplifer ideal for single-supply applications that require a high common-mode voltage range. The internal resistors and ESD circuitry at the inputs also provide overvoltage protection to the op amp.The AD8278 and AD8279 can be used as difference amplifiers with G = ½ or G = 2. They can also be connected in a high precision, single-ended configuration for non inverting and inverting gains of −½, −2, +3, +2, +1½, +1, or +½. The AD8278 and AD8279 provide an integrated precision solution that has a smaller size, lower cost, and better performance than a discrete alternative.The AD8278 and AD8279 operate on single supplies (2.0 V to 36 V) or dual supplies (±2 V to ±18 V). The maximum quiescent supply current is 200 μA, which is ideal for battery-operated and portable systems. For unity-gain difference amplifiers with similar performance, refer to theAD8276andAD8277data sheets.The AD8278 is available in the space-saving 8-lead MSOP and SOIC packages, and the AD8279 is offered in a 14-lead SOIC package. Both are specified for performance over the industrial temperature range of −40°C to +85°C and are fully RoHS compliant.ApplicationsVoltage measurement and monitoringCurrent measurement and monitoringInstrumentation amplifier building blockPortable, battery-powered equipmentTest and measurement